Abdominal pain, sometimes called ‘K cramps’, have been reported by people who have taken ketamine for a long time. The urinary tract, from the kidneys down to the bladder, can also be affected and incontinence (uncontrolled peeing) may also develop. Although stopping using ketamine can help, sometimes the damage can be so serious that the bladder needs surgical repair or even removal. This can be very painful and the pee can be blood-stained. Ketamine can cause serious bladder problems, with the urgent and frequent need to pee. Because you don't feel pain properly when you've recently taken ketamine, you can injure yourself and not know you've done it. Because of the body’s loss of feelings, paralysis of the muscles and the mind’s loss of touch with reality, you can be left vulnerable to hurting yourself or being hurt by others. It can make you feel sick, and it can cause damage to your short- and long-term memory. It can make you confused, agitated, delirious and disconnected from reality. Ketamine can increase your heart rate and blood pressure. Taking ketamine can be fatal, particularly if it is mixed with other drugs. 
Ketamine is a very powerful anesthetic that can cause serious harm.
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